Police are appealing for information after the break-in at Kingston Hill, in Kingston Blount, near Chinnor, overnight between Sunday, March 10, and Monday March 11.
Among the stolen goods are an 18th Century George III sideboard valued at £4,500, a silver fruit bowl engraved "Kingston Blount" worth £2,000 and various items of silver tableware, some of which has a Hanoverian pattern.
The house was occupied at the time of the burglary and detectives believe the thieves escaped through the rear garden.
Pc Dave Edwards, of Didcot police, said: "I'm keen to speak to anyone who saw any suspicious activity taking place in or around Kingston Hill on the night in question. Kingston Blount is a small village, but very close to junction six of the M40.
"I would also like to appeal to any antique dealers who come into contact with anything they find suspicious, or any antiques with the distinctive Hanoverian markings to contact us."
Anyone with information should all Pc Edwards on 08458 505505 or Crimestoppers on 0800 555111